How is low progesterone treated? Treatment options for progesterone supplementation include: creams and gels, which can be used topically or vaginally. suppositories, which are commonly used to treat low progesterone that causes fertility problems. oral medications, like Provera. Can progesterone cause insomnia? This hormone is considered a soporific hormone, meaning that it can induce early sleep onset. As a result, higher levels of progesterone can lead to both excessive daytime sleepiness and disrupted sleep at night. Hormonal changes may cause a pregnant woman to develop insomnia symptoms.
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